RNA Interference Technology : From Basic Science to Drug Development
Editorial Reviews
Review
'This book is very timely. The chapters on the basics of RNAi, siRNA and miRNAs are an excellent summary of the recent origins of this topic and the various sections dealing with RNAi technology provided comprehensive background material. I am sure that, even with the rapid progress in RNAi , this book will be useful for both newcomers to the field wishing to get an overview and for experienced researchers looking for a summary of published information.' David Baulcombe, The Sainsbury Laboratory, Norwich UK
'Only six years ago Fire and Mello discovered RNAi, as a funny effect in little worms. Now the whole world wants to know about it. In this book Krishnarao Appasani got an alll-star crowd of specialists to introduce RNAi: its history, biology, application in genomics research, and possible therapeutic use. Warmly recommended.' Ronald Plasterk, Hubrecht Laboratories, Utrecht, the Netherlands
'A comprehensive treatise on RNA interference has long been needed. That need has now been filled with this book, which places RNAi and its potential squarely in the context of the post human genome era. The successful juxtaposition of the many aspects of RNAi biology and technology should serve to stimulate creative thought across the many diverse disciplines affected by the RNAi revolution.' Ronald K. Scheule, Ph.D., Genzyme Corporation
Book Description
RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. RNAi is used to block the expression of genes and create phenotypes that can potentially yield clues about the function of these genes. In the postgenomic era, the elucidation of the physiological function of genes has become the rate-limiting step in the quest to develop 'gene-based drugs' and RNAi could potentially play a pivotal role in the validation of such novel drugs. In this cutting-edge overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications. Leading experts from both academia and industry have contributed to this invaluable reference for graduate students, post-docs and researchers from academia wanting to initiate RNAi research in their own labs, as well as for those working in research and development in biotech and pharmaceutical companies who need to understand this emerging technology.
RNA Interference Technology : From Basic Science to Drug Development
RNA Interference Technology: From Basic Science to Drug Development,Andrew Fire,Marshall Nirenberg,Krishnarao Appasani,Cambridge University Press,0521836778,Gene silencing,Life Sciences - Genetics & Genomics,Science,Science/Mathematics,Small interfering RNA,Genetics (non-medical),Medical / Biotechnology
Buy Best Books:
Recommended Books